Highly cited cancer researcher logs 8th, 9th retractions

Bharat Aggarwal

Bharat Aggarwal

Bharat Aggarwal, a in a great degree cited cancer researcher who retired finally year from MD Anderson, has logged couple retractions following an investigation into his drudge, bringing his total to nine.

Aggarwal has threatened to supplicate us in the past, and told us that MD Anderson has been investigating his drudge. Earlier this year, Biochemical Pharmacology retracted seven studies of that he is the only common contriver, noting the “data integrity has come to be questionable.” Now, he’s earned brace more retractions in Molecular Pharmacology, as well-as; not only-but also; not only-but; not alone-but for “inappropriate” or “unacceptable” figure manipulation.

Both of the notices are paywalled (tsk, tsk). Here’s individual for “Flavopiridol suppresses tumor necrosis agent-induced activation of activator protein-1, c-Jun N-extremity kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits statement of antiapoptotic gene products, and enhances apoptosis through cytochrome c deliverance and caspase activation in human myeloid cells:”

Following some internal investigation, the article referenced over has been found to contain inappropriate image manipulation in Figure 5A. In joining, the beta-actin loading controls shown in Figure 4A and B are selfsame, although they are presented as divided blots. Molecular Pharmacology has retracted this particular.

The 2008 paper has been cited 27 ages, according to Thomson Reuters Web of Science.

And here’s the intelligence for “A novel pentamethoxyflavone from the top to the bottom of-regulates tumor cell survival and proliferative and angiogenic gene products through inhibition of IκB kinase activation and sensitizes tumor cells to apoptosis by cytokines and chemotherapeutic agents:”

Following each internal investigation, Figures 1 and 3 of the article referenced aloft have been found to contain offensive image manipulation. Molecular Pharmacology has retracted this substance.

The 2011 paper has been cited five spells.

Aggarwal is now up to nine retractions, six corrections, couple unexplained withdrawals, and two Expressions of Concern.

Aggarwal has been cantankerous by allegations of misconduct for years, such as on one blog that arena multiple papers.

Interestingly enough, Aggarwal’s memory tops the Pharmacology and Toxicology section of Thomson Reuters Web of Science’s 2015 catalogue of The World’s Most Influential Scientific Minds (view p. 89). Seven of Aggarwal’s papers be in possession of each been cited at least 1,000 ages, and the list is presented alphabetically.

Earlier this year, a narration from MD Anderson told us he had retired:

MD Anderson Cancer Center is committed to the highest standards of scientific integrity. Any scientific work that does not pertain to the highest standards of philosophical integrity is not acceptable. MD Anderson in like manner supports organizations and journals, like Biochemical Pharmacology, at the time questions of scientific integrity have been raised and they obtain determined that steps must be taken to reclaim the scientific record and ensure scientific integrity.

Contacted today, the institution referred us to his lawyer:

Bharat B. Aggarwal, Ph.D., is not at all longer employed at The University of Texas MD Anderson Cancer Center. In advancement of our institutional policies and founded on law, MD Anderson does not make notes on these sorts of inquiries. However, questions respecting Dr. Aggarwal may be directed to his attorney, Paul S. Thaler at Cohen Seglias Pallas Greenhall & Furman PC, by means of his request.

Aggarwal is now ostensibly the founding director of the Anti-conflagration Research Institute in San Diego. We did a probe for the facility, but were incompetent to find a website.

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