Sugar may be as damaging to the brain as extreme abuse

Sugar may have ~ing as damaging to the brain as extreme abuse

Posted by Big Rat put ~ Campus on Feb 16, 2016 in Rat News | Subscribe

We wholly know that cola and lemonade aren’t vast for our waistline or our dental health, but our new study on rats has diffuse light on just how much injure sugary drinks can also do to our brain.

The changes we observed to the sphere of the brain that controls emotional behaviour and cognitive performance were more extensive than those caused by extreme early life stress.

It is known that harmful experiences early in life, such like extreme stress or abuse, increase the risk of poor mental health and psychiatric disorders later in life.

The consist of of traumatic events (accidents; witnessing each injury; bereavement; natural disasters; physical, sexual and emotional impose on; domestic violence and being a sufferer of crime) a child is exposed to is associated by elevated concentrations of the major emphasis hormone, cortisol.

There is also ground of belief that childhood maltreatment is associated with reduced brain volume and that these changes may have existence linked to anxiety.

What we raise

Looking at rats, we examined whether the impression of early life stress on the brain was exacerbated ~ the agency of drinking high volumes of sugary drinks hind weaning. As females are more likely to experience adverse life events, we carefully read female Sprague-Dawley rats.

To pattern early life trauma or abuse, in the pattern of rats were born half of the litters were exposed to limited nesting important from days two to nine after birth. They then returned to legitimate bedding until they were weaned. The limited nesting alters motherly behaviour and increases anxiety in the progeny later in life.

Sugar could have existence more damaging to the brain than trauma. from

At weaning, moiety the rats were given unlimited to way of approach to low-fat chow and sprinkle and calender to drink, while their sisters were given chow, take in ~ and a 25% sugar solution that they could fix upon to drink. Animals exposed to in season life stress were smaller at weaning, only this difference disappeared over time. Rats consuming compliment in both groups (control and stress) ate more calories over the experiment.

The rats were followed until they were 15 weeks intelligent, and then their brains were examined. As we apprehend that early life stress can drive firmly together mental health and function, we examined a ingredient of the brain called the hippocampus, that is important for both memory and significance. Four groups of rats were studied – control (no stress), control rats tippling sugar, rats exposed to stress, and rats exposed to significance who drank sugar.

We found that deep-seated consumption of sugar in rats who were not stressed produced homogeneous changes in the hippocampus as seen in the rats who were stressed yet not drinking sugar. Early life inclemency exposure or sugar drinking led to diminish expression of the receptor that binds the major stress hormone cortisol, which may crave the ability to recover from exposure to a stressful situation.

Health recent accounts in pictures


Multiple Sclerosis offspring cell treatment ‘helps patients walk again’

A modern treatment for multiple sclerosis (MS) has enabled some patients to walk again by “rebooting” their immune systems. As member of a clinical trial at Sheffield’s Royal Hallamshire Hospital involving encompassing 20 patients, scientists used stem cells to support out a bone marrow transplant. The mode known as an autologous haematopoietic shoot cell transplant (HSCT) works by using chemotherapy to eradicate the area of the immune a whole which causes MS


Dementia patients left independently of painkillers and handcuffed to bed

Dementia patients actual observation a ‘shocking’ variation in the characteristic of hospital care they receive over England, a charity has warned. Staff using exuberant force and not giving dementia patients the make right pain medication were among the tools and materials outlined in a new report ~ the agency of The Alzheimer’s Society, to fall exactly together with the launch of Fix Dementia Care campaign


Cancer jeopard ‘increased’ by drinking more than single glass of wine or pint of beer through day

Drinking more than one glass of wine or pint of beer a ~light increases the risk of developing cancer, according to therapeutical experts. New guidelines for alcohol decline by the UK published by first medical officers warn that drinking some level of alcohol has been linked to a compass of different cancers. The evidence from the Committee on Carcinogenicity (COC) overturns the oft-held behold that a glass of red wine have power to have significant medical benefits for as well-as; not only-but also; not only-but; not alone-but men and women


Vaping ‘~t one better’ than smoking regular cigarettes

Vaping could be “no better” than smoking established cigarettes and may be linked to cancer, scientists be obliged found. The study which showed that vapour from e-cigarettes be possible to damage or kill human cells was publsihed at the same time that the devices are to be rolled revealed by UK public health officials at the same time that an aid to quit smoking from 2016. An estimated 2.6 the masses people in the UK currently practice e-cigarettes


Rat-bamboozle fever

A teenager was hospitalised and left unable to move after she developed the extraordinary rat-bite fever disease from her fit of peevishness rodents which lived in her bedroom. The teenager, who has not been named, was taken to hospital later than she complained of a pain in her appropriate hip and lower back which later made her expressionless, according to the online medical magazine BMJ Case Reports. She suffered for two weeks with an intermittent febrile affection, nausea and vomiting and had a pink rash on her hands and feet. The teenager, who had numerous pets including a dog, cat, stallion and three pet rats, has from the time of made a full recovery after undergoing a manner of proceeding of antibiotics. Blood tests showed that she was infected with for streptobacillus moniliformis – the greatest in quantity common cause of rat-bite agitation. One of her three pet rats concoct dead in her room for three weeks face to face with her symptoms showed


Taking antidepressants in pregnancy ‘could double the put to hazard of autism in toddlers’

Taking antidepressants for the period of pregnancy could almost double the expose to danger of a child being diagnosed with autism in the first years of life, a major study of nearly 150,000 pregnancies has suggested. Researchers have found a link between women in the later stages of pregnancy who were prescribed united of the most common types of antidepressant drugs, and autism diagnosed in children while suffering seven years of age


Warning through Calpol

Parents have been warned that giving children paracetamol-based medicines similar as Calpol and Disprol too often could lead to serious health issues later in life. Leading paediatrician and professor of common paediatrics at University College London, Alastair Sutcliffe, declared parents were overusing paracetamol to banquet mild fevers. As a result, the put to hazard of developing asthma, as well while kidney, heart and liver damage is heightened


Fat waste from pancreas ‘can reverse’ furniture of type-2 diabetes

Less than half a teaspoon of fat is altogether that it takes to turn someone into a proto~-2 diabetic according to a study that could overturn bargained for wisdom on a disease affecting not remotely 3 million people in Britain. Researchers wish found it is not so plenteous the overall body fat that is significant in determining the onset of protoplast-2 diabetes but the small whole of fat deposited in the pancreas, the endocrine organ responsible for insulin production


Potatoes impoverish risk of stomach cancer

Scientists acquire found people who eat large amounts of destitute of color vegetables were a third less credible to contract stomach cancer. The study, undertaken ~ means of Chinese scientists at Zhejiang University, base eating cauliflower, potatoes and onions reduces the contingency of contracting stomach cancer but that beer, spirit, salt and preserved foods increased a person’s exposure to harm of the cancer


Connections between brain cells destroyed in early stages of Alzheimer’s ail

Scientists have pinpointed how connections in the brain are destroyed in the soon stages of Alzheimer’s disease, in a study that it is hoped will help in the development of treatments for the debilitating plight. At the early stages of the growth of Alzheimer’s disease the synapses – what one. connect the neurons in the brain – are destroyed, according to researchers at the University of New South Wales, Australia. The synapses are essential for brain function, particularly learning and forming memories


Sugar duty

The Government should introduce a sweeten tax to prevent an “obesity crisis” from crippling the NHS, a older Conservative MP and former health ad~ has said. Dr Dan Poulter believes that the suit for increased taxes on unhealthy sweet products was “increasingly compelling”


Cancer breakthrough offers newly come hope for survivors rendered infertile by chemotherapy

A potentially “phenomenal” philosophical breakthrough has offered fresh hope to cancer patients rendered infertile through chemotherapy. For the first time, researchers managed to renew ovaries in mice affected by chemotherapy to such a degree that they were able to have offspring. The scientists now plan to break ground clinical trials to see if the technique, which involves the use of stem cells, faculty of volition also work in humans by using umbilical line material and possibly stem cells taken from human embryos, allowing that regulators agree


Take this NHS discriminative characteristic to find out if you be favored with a cancerous mole

An interactive ordeal could help flag up whether you should solicit advice from a health professional conducive to one of the most common types of cancer. The proof is available on the NHS Choices website and reveals whether you are at peril from the disease and recommends if you should seek help. The dike self-assessment factors in elements like as complexion, the number of general condition of affairs you have been severely sunburnt and whether skin cancer runs in your family. It furthermore quizzes you on the number of moles you own and whether there have been a single one changes in appearance regarding size, mould and colour


Health apps approved ~ the agency of NHS ‘may put users at risk of identity theft’

Experts have warned that some apps do not adequately protect exterior information


A watchdog has said that care visits must last longer

The National Institute in opposition to Health and Care Excellence (Nice) said home help visits of less than 30 minutes were not pleasing unless part of a wider package of support


Pendle in Lancashire tops strip of five most anxious places to live in the UK

Pendle in Lancashire has been named the in the greatest degree anxious place to live in the UK, as long as people living in Fermanagh and Omagh in Northern Ireland be seized of been found to be the happiest


Ketamine could be used as anti-depressant

Researchers at the University of Auckland before-mentioned monitoring the effects of the put ~s into on the brain has revealed neural pathways that could prosper the development of fast-acting medications.
Ketamine is a synthetic come to terms used as an off anaesthetic and analgesic mix with ~s, but is commonly used illegally being of the kind which a hallucinogenic party drug.
Dr Suresh Muthukumaraswamy, a older researcher at the university and a member of the institution’s Centre during the term of Brain Research, used the latest technology in brain imaging to inquire into what mechanisms ketamine uses to exist active in the human brain


A prosthetic artisan that lets people actually feel from one side

The technology lets paralysed people be conscious of being actual sensations when touching objects — including of little weight taps on the mechanical finger — and could have existence a huge breakthrough for prosthetics, according to its makers. The tool was used to permit a 28-year-old man who has been paralysed with a view to more than a decade. While prosthetics be favored with previously been able to be controlled soon from the brain, it is the first time that signals have been luckily sent the other way


The biggest ground of early death in the universe is what you eat

Unhealthy erosive has been named as the principally common cause of premature death around the globe, new data has revealed. A worthless diet – which involves eating too few vegetables, fruits, nuts and grains and in addition much red meat, salt and sweeten – was shown to be a bigger killer than smoking and pure spirit


Scientists develop blood test that estimates how quickly people duration of existence

Scientists believe it could be used to divine a person’s risk of developing Alzheimer’s sickness as well as the “youthfulness” of donated organs on this account that transplant operations. The test measures the vital power of certain genes which the researchers put confidence in is an accurate indication of a person’s “biological age”, what one. may be younger or older than their not merely supposed or fancied chronological age


Aspirin could serve boost therapies that fight cancer

The latest therapies that measure swords cancer could work better when combined by aspirin, research has suggested. Scientists from the Francis Crick Institute in London assume the anti-inflammatory pain killer suppresses a cancer atom that allows tumours to evade the body’s immune defences.
Laboratory tests obtain shown that skin, breast and bowel cancer cells ~times generate large amounts of this indivisible particle, called prostaglandin E2 (PGE2).
But Aspirin is unit of a family of drugs that sends messages to the brain to make steady production of PGE2 and this means cancer cells can be attacked through the body’s natural defences

Another gene that is influential for the growth of nerves, Neurod1, was in addition reduced by both sugar and stress. Other genes important for the progress of nerves were investigated, and fair drinking sugar from a young mature years was sufficient to reduce them.

The rats were exposed to dark sugar intakes during development, and the pack together of the sugar is worrying in the manner that it may affect brain development, even if further work is required to proof this.

In this study, combining sweeten intake and early life stress did not originate further changes in the hippocampus, excepting whether this remains the case immersing time is unclear.

What does this servile for us?

The changes in the brain induced ~ dint of. sugar are of great concern given the to multuous consumption of sugar-sweetened beverages, with particularly high consumption in children stricken in years nine to 16 years. If resembling processes are at play in humans to what was found in our rat study, reducing the gradual wasting of sugar across the community is weighty.

The fact that drinking sugar or exposure to early life stress reduced the assertion of genes critical for brain increase and growth is of great touch. While it is impossible to transact such studies in humans, the brain circuits controlling stress responses and feeding are conserved from one side of to the other species.

People who were exposed to seasonable life trauma have changes in the conformation of their hippocampus. In humans, those consuming the ~ numerous “western” diet had smaller hippocampal volumes, in row with data from animal models.

Taken side by side, these findings suggest future work should consider possible long-term effects of boastful sugar intake, particularly early in life, forward the brain and behaviour.

Jayanthi Maniam, Research Associate, UNSW Australia and Margaret Morris, Professor of Pharmacology, Head of Pharmacology, UNSW Australia

This branch was originally published on The Conversation. Read the type article.

More about:


Health tidings

food and drink news

Article spring: of address/health-and-families/health-news/flatter-may-be-as-damaging-to-the-brain-because-extreme-abuse-a6876896.html

Related posts:

Sugar Is Making Us Stupid

Diabetes: Conversion of skin cells to extend insulin could lead to new treatments

Vaccine-like management could one day be used to preclude cancer, study suggests

… other posts by Big Rat on Campus

Tags: Pet, fit of peevishness rat, pet rats, Pets, Rat…, Rats


laid bare all | close all

Rat Shopping

Mrs. Frisby and the Rats of NIMH (11)

Rat Books (11)

Rat Cage Accessories (10)

Rat Cages (19)

Rat Food (7)

Rat Mouse Pads (15)

Rat Novelty Items (12)

Rat Toys (7)

Toy Rats (5)

Rat Product Reviews

Book Reviews (0)

Cage Reviews (1)

Food_Reviews (0)

Toy Reviews (0)

Video Reviews (0)

Rat Information

Rat Answers (769)

Rat Articles (6)

Rat News (1,183)

Rat Videos (10)

Along Animal Ball Cage Care Carrier Chinese Come computer peer pad Decorated Female Ferret Food Frisby Guide Hardcover Have Home Kaytee Marshall Mega mega globe mouse mouse pad Mrs. NIMH Paperback Pet angry mood rat pet rat cage pet rats favorite rat videos Pets Play Rat… rat cage Rat Computer Mouse Pad rat mouse pad Rats Rodent Sign Super Training What by Cage Reviews (1)
Childrens Books (4)
Mrs. Frisby and the Rats of NIMH (11)
Rat Answers (769)
Rat Articles (6)
Rat Books (11)
Rat Cage Accessories (10)
Rat Cages (19)
Rat Food (7)
Rat Mouse Pads (15)
Rat News (1,183)
Rat Novelty Items (12)
Rat Toys (7)
Rat Videos (10)
Toy Rats (5)

Feedjit Live Blog Stats

RatChatter forward Facebook

Train Signal can bring you Microsoft training whether you’re a home user, calling user, an enthusiast, or an administrator. We offer Office 2007 Training that is large and fun! Click Here!

Classic Styles Like No Other – Playtex at

Facebook during up to date news regarding work updates, forum news, competitions and accord. aways.

Both comments and pings are currently closed.