323 Statins & Vitamin K2

Back in April 2012 I wrote relative to the effect of statin (cholesterol cloudy) drugs on Co-enzyme Q10 and muscle pang [#159]. Later, in December 2014 [#299] I showed that vitamin D side by side with CoQ10 relieves statin-induced myalgia (SIM). In the arrangement I wrote “If I was taking a statin drug, in addition to supplementing through Q10, I would make sure my D levels were adequate”. New study indicates that statin users should ~ together K2 to their list of supplements in the manner that well.

A recent discovery, discussed ~ means of Okuyama et al in the March 2015 Expert Review of Clinical Pharmacology, is that statin drugs interdict the synthesis of vitamin K2. I take previously discussed [#149] how K2 is vital for directing the calcium from your diet and supplements into your bones instead of your joints and arteries. A 2009 study from Utrecht, Netherlands, had shown that a capital intake of K2 reduced the peril of coronary heart disease. It at this time appears that, ironically, statins, by inhibiting K2 composition, could be promoting atherosclerosis, the highly condition they are supposed to impede. The same study (Okuyama et al, 2015) added that statins, also inhibit the synthesis of glutathione peroxidase, the highly rectified antioxidant I discussed in two columns in May. Another study published in June 2011 in JAMA concluded that haughty dose statin therapy increases risk of diabetes compared to moderate dose therapy.

How could it be possible for drugs with side personal estate like these to be so common (taken by 1 in 4 Americans mature years 45 and over)? Are the benefits certainly worth the risks? An investigation into this investigation was published by Diamond & Ravnskov in the same March 2015 issue of Expert Review of Clinical Pharmacology. They conclude:

“…although statins are active at reducing cholesterol levels, they failed to stoutly improve cardiovascular outcomes… Statin advocates obtain … [deceptively amplified] the nugatory beneficial effects of statins [and] succeeded in minimizing the moment of the numerous adverse effects of statin management.”Please follow the links in the regions of the dead, and read these articles for yourself. Then discuss them with your physician and pharmacist. If you decide that statin therapy is muffle indicated, then consider supplementing with CoQ10, and vitamins D and K2.


Okuyama, H et al Expert Rev Clin Pharmacol 2015 Mar:8(2):189-99 Statins whet atherosclerosis and heart failure: pharmacological mechanisms [take out of context]

Gast, GC et al Nutr Metab Cardiovasc Dis 2009 Sep:19(7):504-10 A distinguished menaquinone intake reduces the incidence of coronary inner part disease [abstract]

Diamond DM, Ravnskov U. Expert Rev Clin Pharmacol 2015 Mar:8(2):201-10 How statistical deception created the appearance that statins are guarded and effective in primary and inferior prevention of cardiovascular disease.[abstract]

For greater degree of information on this or other spontaneous health topics, stop in and subject of discourse to Stan; for medical advice consult your licensed health practitioner.

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