A novel study has demonstrated that menthol acts in compound with nicotine to desensitize can have ~ing harmful for lungs.
Senior author Gerard Ahern, PhD, ~y associate professor of pharmacology at Georgetown University Medical Center (GUMC), related that in addition to desensitizing the receptors in the lung and airways, menthol appears to heavy or prevent the recovery of sensitivity about the first insult, likely placing the receptors in a desensitized state.
Study co-author, Kenneth Kellar, PhD, a professor of pharmacology at GUMC, afore~ that these receptors were also set in the brain, but they did not understand yet what effect menthol had attached those receptors, or whether they grant, in any way, to nicotine immersion.
Ahern and his colleague say their study provides a more fully understanding of how menthol affects the exercise of the a34 receptor, one of the greatest number prevalent nicotinic acetylcholine receptors expressed in the peripheral spirited system. These receptors are expressed in airway sensory nerves for the re~on that well as other neurons.
Ahern added that the conclusion may be that menthol in the mien of nicotine may reduce the excitation enough that a smoker can inspire more deeply, bringing not just nicotine still toxic smoke products farther into the lungs.
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